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CD8 (EP334), RMab
| SKU: |
BSB 2845 |
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Antibody type:
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Rabbit Monoclonal
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Clone:
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EP334
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Isotype:
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IgG
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Concentrate Dilution:
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1:50-1:200
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Localization:
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Membranous
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Tissue Control:
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Tonsil, Lymph Node, Liver, Colon
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Species Reactivity:
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Human
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Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
CD8 is a transmembrane glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). Like the TCR, CD8 binds to a major histocompatibility complex (MHC) molecule that is specific for the Class I MHC protein. To function, CD8 forms a dimer, consisting of a pair of CD8 chains. The most common form of CD8 is composed of a CD8-α and CD8-β chain, both members of the immunoglobulin superfamily with an immunoglobulin variable (IgV)-like extracellular domain connected to the membrane by a thin stalk, and an intracellular tail.
CD8 antibody is a T-cell marker for the detection of cytotoxic/suppressor cells of blood lymphocytes. CD8 is also detected on NK cells, most thymocytes, a subpopulation of null cells and bone marrow cells. This antibody is used to distinguish between reactive and neoplastic T-cells.
Presentation
CD8 antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: CD8B, CD8B1, CD8A, MAL, anti-CD8, anti CD8, anti-CD8A, anti CD8A, T-lymphocyte differentiation antigen T8/Leu-2, anti-MAL, anti MAL, anti-, anti , anti-T-lymphocyte differentiation antigen T8/Leu-2, anti T-lymphocyte differentiation antigen T8/Leu-2, CD8 antigen beta polypeptide 1 p37, CD8b molecule, Leu2, LY3, LYT3, MGC119115, T lymphocyte surface glycoprotein beta chain, T cell surface glycoprotein CD8 beta chain, CD8, CD8 antigen alpha polypeptide p32, CD8a molecule, Leu2 T lymphocyte antigen, OKT8 T cell antigen, p32, T cell co receptor, T cell antigen Leu2, T cell surface glycoprotein CD8 alpha chain, T lymphocyte differentiation antigen T8 Leu 2, T8 T cell antigen, P37
Specification Sheets
Safety Data Sheets
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| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 2845 | $231.00 |
| Presentation: 7 ml Predilute | BSB 2846 | $419.00 |
| Presentation: 15 ml Predilute | BSB 2847 | $758.00 |
| Presentation: .1 ml Concentrate | BSB 2848 | $204.00 |
| Presentation: .5 ml Concentrate | BSB 2849 | $548.00 |
| Presentation: 1 ml Concentrate | BSB 2850 | $956.00 |
| Presentation: Control Slides [5] | BSB-9112-CS | $77.00 |
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