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Claudin-5 (EP224), RMab

Presentation:

Price: $251.00

SKU:	BSB 2398
Antibody type:	Rabbit Monoclonal
Clone:	EP224
Isotype:	IgG
Concentrate Dilution:	1:25-1:100
Localization:	Cytoplasmic, Membranous
Tissue Control:	Liver, Vascular Tissue, Placenta
Species Reactivity:	Human

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Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

Claudin-5 is a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction (TJ) strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Claudin-5 is an endothelial cell-specific component of TJ strands. Mutations in Claudin-5 have been found in patients with velocardiofacial syndrome.

Claudin-5 antibody labels endothelial cells and has been used as a marker for endothelial lesions. Claudin-5 is also found in bronchial and lung epithelial cells. In tumors, Claudin-5 expression has been found in lung adenocarcinoma and squamous carcinoma. In serous ovarian adenocarcinoma, increased Claudin-5 expression is associated with aggressive behavior.

Presentation

Claudin-5 antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Synonyms: Claudin 5, CLDN5, claudin5, anti-claudin-5, anti claudin-5, anti-CLDN5, anti CLDN5, anti-claudin 5, anti-claudin5, anti claudin 5, anti claudin5, AWAL, BEC1, CPETRL1, TMDVCF, TMVCF, Transmembrane protein deleted in VCFS, transmembrane protein deleted in velocardiofacial syndrome

Specification Sheets

IVD - CE

Safety Data Sheets

SDS

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Option	SKU	Price
Presentation: 3 ml Predilute	BSB 2398	$251.00
Presentation: 7 ml Predilute	BSB 2399	$450.00
Presentation: 15 ml Predilute	BSB 2400	$819.00
Presentation: .1 ml Concentrate	BSB 2401	$279.00
Presentation: .5 ml Concentrate	BSB 2402	$613.00
Presentation: 1 ml Concentrate	BSB 2403	$938.00
Presentation: Control Slides [5]	BSB-9120-CS	$77.00