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Cytokeratin OSCAR (OSCAR), MMab
SKU: |
BSB 6177 |
Antibody type:
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Mouse Monoclonal
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Clone:
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OSCAR
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Isotype:
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IgG2a
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Concentrate Dilution:
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1:50-1:200
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Localization:
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Cytoplasmic
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Tissue Control:
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Breast, Liver, GI, Prostate,
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Species Reactivity:
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Human
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Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
Cytokeratin OSCAR is a mouse monoclonal antibody for immunohistochemistry from Bio SB. Cytokeratin OSCAR is well-suited to distinguish epithelial carcinoma from non-epithelial malignancies and is used to aid epithelial tumor classification. Cytokeratin OSCAR identifies a number of bands corresponding to cytokeratins 7, 8, 18 and 19 (additional bands – cytokeratins – may also be detected). This antibody has been used to characterize the source of various neoplasms and to study the distribution of keratin-containing cells in epithelia during normal development and during the development of epithelial neoplasms.
In normal tissues, Cytokeratin OSCAR is reactive with most epithelial types tested including bile ducts and hepatocytes in liver, bladder epithelium, breast ducts, bronchial epithelium, endometrium, follicular dendritic cells of lymph node and tonsil, intestinal epithelium of the stomach, duodenum, ileum, colon, rectum, pancreas, ovarian epithelium, pancreatic acini, pituitary acini, pneumocytes, prostate, thyroid and skin. In tumors, OSCAR is reactive with most carcinomas including breast, TCC, RCC, lung, endometrial CA, prostate CA, ovarian CA, HCC, colorectal CA, stomach CA and thyroid CA. It is negative in certain normal tissues including brain, lymphocytes and all cells of hematolym-phoid origin, muscle, brain, nerves, endothelium and in certain tumors including melanoma, sarcoma, lymphoma, PNET/Ewing’s and GIST. This antibody has shown high sensitivity in recognizing epithelial cells and carcinomas.
Presentation
Cytokeratin OSCAR antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: cytokeratin oscar, ck oscar, ckoscar, anti-ck oscar, anti-ckoscar, anti-cytokeratin oscar, anti ck oscar, anti cytokeratin oscar, keratin oscar, anti-keratin oscar, anti keratin oscar
Specification Sheets
Safety Data Sheets
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Option | SKU | Price |
Presentation: 3 ml Predilute | BSB 6177 | $142.00 |
Presentation: 7 ml Predilute | BSB 6178 | $260.00 |
Presentation: 15 ml Predilute | BSB 6179 | $464.00 |
Presentation: .1 ml Concentrate | BSB 6180 | $167.00 |
Presentation: .5 ml Concentrate | BSB 6181 | $362.00 |
Presentation: 1 ml Concentrate | BSB 6182 | $602.00 |
Presentation: Control Slides [5] | BSB 6183 | $77.05 |
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