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GCDFP-15 (23A3), MMab

Presentation:

Price: $140.00

SKU:	BSB 5554
Antibody type:	Mouse Monoclonal
Clone:	23A3
Isotype:	IgG2a
Concentrate Dilution:	1:100-1:500
Localization:	Cytoplasmic
Tissue Control:	Breast, Sweat Glands in Skin, Breast Carcinoma
Species Reactivity:	Human, Rat

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Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

Gross Cystic Disease is a common premenopausal disorder in which gross cysts are the predominant pathologic lesion. It is characterized by production of a fluid secretion which accumulates in the breast cysts. Gross Cystic Disease fluid is a pathologic secretion from breast composed of several glycoproteins, including a unique 15 kDa monomer protein, GCDFP-15. The cells within the body that produce GCDFP-15 appear to be restricted primarily to those with apocrine function such as breast cysts and in apocrine glands in the axilla, vulva, eyelid, and ear canal.

Studies have found GCDFP-15 antibody to be a highly specific and sensitive marker for breast cancer. Approximately 70% of breast carcinomas stain positive with antibody to GCDFP-15. In contrast, Colorectal Carcinomas, as well as Mesotheliomas, do not stain with this antibody. Lung Adenocarcinomas rarely stain with this antibody.

Presentation

GCDFP-15 antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Synonyms: GCDFP 15, GCDFP15, Pip, GP17, mSMGP, gross cystic disease fluid protein 15, gcdfp-15, gcdfp15, gcdfp 15, anti-GCDFP 15, anti-GCDFP-15, anti GCDFP 15, anti GCDFP-15

Specification Sheets

IVD - CE

Safety Data Sheets

SDS

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Option	SKU	Price
Presentation: 3 ml Predilute	BSB 5554	$140.00
Presentation: 7 ml Predilute	BSB 5555	$251.00
Presentation: 15 ml Predilute	BSB 5556	$450.00
Presentation: .1 ml Concentrate	BSB 5557	$142.00
Presentation: .5 ml Concentrate	BSB 5558	$394.00
Presentation: 1 ml Concentrate	BSB 5559	$617.00
Presentation: Control Slides [5]	BSB-9193-CS	$77.00