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Granzyme B (EP230), RMab

Presentation:

Price: $208.00

SKU:	BSB 2405
Antibody type:	Rabbit Monoclonal
Clone:	EP230
Isotype:	IgG
Concentrate Dilution:	1:25-1:100
Localization:	Cytoplasmic (Granular)
Tissue Control:	Liver, Testis, Cervix, Tonsil, Lymph Node
Species Reactivity:	Human

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Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

Granzymes are exogenous serine proteases that are released by cytoplasmic granules within cytotoxic T-cells and natural killer cells. Their purpose is to induce apoptosis within virus-infected cells, thus destroying them.

Granzyme B antibody has been useful in diagnosing Natural Killer/T-cell Lymphoma, as well as Anaplastic Large Cell Lymphoma. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin’s Disease.

Presentation

Granzyme B antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Synonyms: anti-granzyme b, anti granzyme b, anti-gb, anti gb, GZMB, granzyme B granzyme 2 cytotoxic T lymphocyte associated serine esterase 1, CCPI, CGL 1, CGL1, CSP B, CSPB, CTLA1, CTSGL1, HLP, SECT

Specification Sheets

IVD - CE

Safety Data Sheets

SDS

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Option	SKU	Price
Presentation: 3 ml Predilute	BSB 2405	$208.00
Presentation: 7 ml Predilute	BSB 2406	$377.00
Presentation: 15 ml Predilute	BSB 2407	$680.00
Presentation: .1 ml Concentrate	BSB 2408	$232.00
Presentation: .5 ml Concentrate	BSB 2409	$509.00
Presentation: 1 ml Concentrate	BSB 2410	$776.00
Presentation: Control Slides [5]	BSB-9201-CS	$99.00