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Kappa Light Chains (BSB-58), MMab

Presentation:

Price: $97.00

SKU:	BSB 5701
Antibody type:	Mouse Monoclonal
Clone:	BSB-58
Isotype:	IgG1/K
Concentrate Dilution:	1:250-1:1000
Localization:	Cytoplasmic
Tissue Control:	Tonsil, Lymph Node
Species Reactivity:	Human, Dog, Cat

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Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

Kappa detects surface immunoglobulin on normal and neoplastic B-cells. In paraffin-embedded tissue, Kappa exhibits strong staining of kappa-positive plasma cells and cells that have absorbed exogenous immunoglobulin. When studying B-cell neoplasms, the determination of light-chain ratios remains the centerpiece. This is sound reasoning because most B-cell Lymphomas express either kappa or lambda light chains, whereas reactive proliferations display a mixture of kappa and lambda-positive cells. If only a single light-chain type is detected, a lympho-proliferative disorder is very likely. Monoclonality is determined by a kappa-lambda ratio greater than or equal to 3:1, a lambda-kappa ratio greater than or equal to 2:1, or a monoclonal population of 75% or more of the total population.

Presentation

Kappa is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Specification Sheets

IVD - CE

RUO

Safety Data Sheets

SDS

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Option	SKU	Price
Presentation: 3 ml Prediluted	BSB 5701	$97.00
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