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MSH6 (44), MMab

Presentation:

Price: $131.00

SKU:	BSB 6142
Antibody type:	Mouse Monoclonal
Clone:	44
Isotype:	IgG1
Concentrate Dilution:	1:50-1:200
Localization:	Nuclear
Tissue Control:	Colon Mucosa, Colon Carcinoma
Species Reactivity:	Human, Rat, Mouse, Dog

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Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

MSH6 is mouse monoclonal antibody (MMab) for immunohistochemistry from Bio SB. MSH6 is a gene commonly associated with Hereditary Non-Polyposis Colorectal Cancer (HNPCC). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset Colorectal Carcinoma and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited Colorectal Cancer in the western world. MSH6 is a mismatch repair gene which is deficient in a high proportion of patients with microsatellite instability (MSI-H).

The MSH6 antibody is useful in screening patients and families for HNPCC. Colon cancers that are microsatellite-unstable have a better prognosis than their microsatellite-stable counterparts.

Presentation

MSH6 antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Synonyms: msh-6, anti msh6, anti-msh6, anti msh-6, gtbp, anti-gdbp, SH6, DNA mismatch repair protein Msh6, G T mismatch binding protein, GTBP, GTMBP, HNPCC5, HSAP, mutS homolog 6 E coli, MutS alpha 160 kDa subunit, p160, sperm associated protein, hMSH6

Specification Sheets

IVD - CE

Safety Data Sheets

SDS

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Option	SKU	Price
Presentation: 3 ml Prediluted	BSB 6142	$131.00
Presentation: 7 ml Prediluted	BSB 6143	$238.00
Presentation: 15 ml Prediluted	BSB 6144	$429.00
Presentation: .1 ml Concentrated	BSB 6145	$160.00
Presentation: .5 ml Concentrated	BSB 6146	$391.00
Presentation: 1 ml Concentrated	BSB 6147	$638.00
Presentation: Control Slides [5]	BSB 6148	$63.00