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PMS2 (EP51), RMab

Presentation:

Price: $266.00

SKU:	BSB 2119
Antibody type:	Rabbit Monoclonal
Clone:	EP51
Isotype:	IgG
Concentrate Dilution:	1:25-1:100
Localization:	Nuclear
Tissue Control:	Colon Mucosa, Colon Carcionma
Species Reactivity:	Human

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Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

PMS2 is a gene that encodes for DNA repair proteins involved in mismatch repair. Carriers of the mismatch repair gene mutations have a high lifetime risk of developing Hereditary Non-Polyposis Colon Cancer (HNPCC) and several other cancers including endometrial cancer due to microsatellite instability (MSI) caused by accumulation of DNA replication errors in proliferating cells. Along with MLH1, MSH2 and MSH6, PMS2 is helpful in diagnosing MSI. Tumors with low-level MSI show unfavorable pathological characteristics compared to tumors with none and tumors with high-level MSI.

Presentation

PMS2 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Specification Sheets

IVD - CE

RUO

Safety Data Sheets

SDS

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Option	SKU	Price
Presentation: 3 ml Prediluted	BSB 2119	$266.00
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Presentation: 15 ml Prediluted	BSB 2121	$773.00
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