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S100A1 (EP184), RMab

Presentation:

Price: $287.10

SKU:	BSB 2161
Antibody type:	Rabbit Monoclonal
Clone:	EP184
Isotype:	IgG
Concentrate Dilution:	1:25-1:100
Localization:	Cytoplasmic, Nuclear
Tissue Control:	Brain, Breast, Thyroid, Tonsil, Pancreas
Species Reactivity:	Human, Predicted: Mouse, Rat

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Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

The S100A1 protein is a member of the S100 family of proteins containing 4 EF-hand calcium-binding motifs in its dimerized form. S100 protiens are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentation. S100A1 may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly and inhibition of protein kinase C-mediated phosphorylation.

In normal tissues, S100A1 antibody is expressed in cardiac muscle, skeletal muscle and neuronal cells. Reduced expression of S100A1 has been implicated in carciomyopathies. It can also be useful in distinguishing between Renal Oncocytomas and Clear Cell Renal Cell Carcinomas (positive) and Papillary Renal Cell Carcinomas (positive) from Chromophobe Renal Cell Carcinomas (negative). It is a specific and sensitive marker for Nephrogenic Adenoma.

Presentation

S100A1 antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Synonyms: anti-s100a1, anti-s100-a1, anti-s100 a1, s100-a1, s100 a1, s100 alpha, anti-s100 alpha, anti s100 alpha, s100-a1, s100a, s100 a

Specification Sheets

IVD - CE

Safety Data Sheets

SDS

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Option	SKU	Price
Presentation: 3 ml Predilute	BSB 2161	$287.10
Presentation: 7 ml Predilute	BSB 2162	$521.40
Presentation: 15 ml Predilute	BSB 2163	$834.90
Presentation: .1 ml Concentrate	BSB 2164	$204.60
Presentation: .5 ml Concentrate	BSB 2165	$455.40
Presentation: 1 ml Concentrate	BSB 2166	$847.00
Presentation: Control Slides [5]	BSB 2167	$67.00