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SOX-2 (RM427), RMab
| SKU: |
BSB-3770-3 |
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Antibody type:
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Rabbit Monoclonal
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Clone:
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RM427
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Isotype:
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IgG
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Concentrate Dilution:
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1:50-1:200
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Localization:
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Nuclear
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Tissue Control:
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Brain, Oligodendroglioma, Squamous Cell Carcinoma
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Species Reactivity:
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Human, Predicted: Mouse
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Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
SRY (sex determining region Y)-box 2, also known as SOX2, is a transcription factor that is essential for maintaining self-renewal, or pluripotency, of undifferentiated embryonic stem cells. It is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach.
SOX-2 antibody is expressed in fetal brain and is used as a marker for multipotential neural stem cells. In tumors, SOX-2 expression is observed in teratoma of the central nervous system, melanoma, testicular germ cell tumor, cervical carcinoma, lung cancer, breast cancer with basal cell phenotype, and squamous cell carcinoma of the gastrointestinal tract. SOX-2 antibodymay be useful in the identification of embryonal carcinoma. In stage I lung adenocarcinomas, SOX-2 seems to be an independent predictor of poor outcome and may help stratify patients at increased risk for recurrence.
Presentation
SOX-2 antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: Sox2, sc365823, Sox 2, anti Sox 2, anti Sox-2, anti Sox2, anti SRY-related HMG-box transcription factor 2, anti-Sox 2, anti-Sox-2, anti-Sox2, anti-SRY-related HMG-box transcription factor 2, SRY-related HMG-box transcription factor 2, ANOP3, MCOPS3, MGC2413, SRY sex determining region Y box 2, SRY related HMG box gene 2, transcription factor SOX 2, transcription factor SOX2
Specification Sheets
Safety Data Sheets
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| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB-3770-3 | $329.00 |
| Presentation: 7 ml Predilute | BSB-3770-7 | $598.00 |
| Presentation: 15 ml Predilute | BSB-3770-15 | $955.00 |
| Presentation: .1 ml Concentrate | BSB-3770-01 | $233.00 |
| Presentation: .5 ml Concentrate | BSB-3770-05 | $523.00 |
| Presentation: 1 ml Concentrate | BSB-3770-1 | $973.00 |
| Presentation: Control Slides [5] | BSB-3770-CS | $77.05 |
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