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Spectrin (RBC2/3D5), MMab

Presentation:

Price: $140.00

SKU:	BSB 5938
Antibody type:	Mouse Monoclonal
Clone:	RBC2/3D5
Isotype:	IgG2b/K
Concentrate Dilution:	1:25-1:100
Localization:	Membranous
Tissue Control:	Bone Marrow, Spleen
Species Reactivity:	Human

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Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

Spectrin is a cytoskeletal protein that lines the intracellular side of the plasma membrane of many cell types in pentagonal or hexagonal arrangements, forming scaffolds and playing an important role in maintenance of plasma- membrane integrity and cytoskeletal structure. The hexagonal arrangements are formed by tetramers of spectrin associating with short actin filaments at either end of the tetramer. These short actin filaments act as junctional complexes, allowing the formation of the hexagonal mesh.

Spectrin is found in the intracellular side of the plasma membrane of many cell types found in muscles, red blood cells and red cell precursors. Spectrin antibody is useful in the diagnosis of Erythroid Leukemias.

Presentation

Spectrin antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Synonyms: SPTAN1, spectrin α II, spectrin alpha II, alpha II spectrin, FLJ44613, fodrin alpha chain, NEAS, Spectrin alpha chain brain, spectrin alpha non erythrocytic 1 alpha fodrin, spectrin non erythroid alpha chain, EIEE5, FLJ17738, SPTA2

Specification Sheets

IVD - CE

Safety Data Sheets

SDS

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Option	SKU	Price
Presentation: 3 ml Predilute	BSB 5938	$140.00
Presentation: 7 ml Predilute	BSB 5939	$254.00
Presentation: 15 ml Predilute	BSB 5940	$454.00
Presentation: .1 ml Concentrate	BSB 5941	$145.00
Presentation: .5 ml Concentrate	BSB 5942	$261.00
Presentation: 1 ml Concentrate	BSB 5943	$457.00
Presentation: Control Slides [5]	BSB 5944	$63.00