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T-Bet / TBX-2 (EP263), RMab
SKU: |
BSB 2601 |
Antibody type:
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Rabbit Monoclonal
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Clone:
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EP263
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Isotype:
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IgG
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Concentrate Dilution:
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1:25-1:100
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Localization:
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Nuclear
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Tissue Control:
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Spleen, Tonsil, Cervix, Liver, Breast
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Species Reactivity:
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Human
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Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
T-bet, a T-box transcription factor, is expressed in CD4+ T-lymphocytes committed to T-helper (Th)1 T-cell development from naïve T-helper precursor cells (Thp) and redirects Th2 T cells to Th1 development.
T-bet antibody is expressed in a significant subset of B-cell lymphoproliferative disorders, particularly at an early stage of B-cell development (precursor B-cell lymphoblastic leukemia/lymphoblastic lymphoma), and B-cell neoplasms derived from mature B cells, including CLL/SLL, marginal zone lymphoma, and hairy cell leukemia. In contrast, B-cell neoplasms derived from pregerminal center or germinal center B-cells, including mantle cell lymphoma, follicular lymphoma, diffuse large B-cell lymphoma, and Burkitt lymphoma are negative for T-bet. Therefore, T-bet antibody should serve as a useful marker for the diagnosis and subtyping of B-cell and T-cell lymphoproliferative disorders.
Presentation
T-bet antibody (TBX2 antibody) is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: T bet, Tbet, Tbx21, anti-T-bet, anti T-bet, anti-T bet, anti-Tbet, anti T bet, anti Tbet, anti-TBX21, anti TBX21, T box 21, T box expressed in T cells, T box protein 21, T box transcription factor TBX21, T cell specific T box transcription factor, T cell specific T box transcription factor T bet, T PET, Tblym, transcription factor TBLYM, TBT1
Specification Sheets
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Option | SKU | Price |
Presentation: 3 ml Predilute | BSB 2601 | $314.00 |
Presentation: 7 ml Predilute | BSB 2602 | $570.00 |
Presentation: 15 ml Predilute | BSB 2603 | $912.00 |
Presentation: .1 ml Concentrate | BSB 2604 | $223.00 |
Presentation: .5 ml Concentrate | BSB 2605 | $524.00 |
Presentation: 1 ml Concentrate | BSB 2606 | $928.00 |
Presentation: Control Slides [5] | BSB-9395-CS | $77.00 |
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