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AMACRacemase / P504S (13H4), RMab

Presentation:

Price: $224.00

SKU:	BSB 5057
Antibody type:	Rabbit Monoclonal
Clone:	13H4
Isotype:	IgG
Concentrate Dilution:	1:25-1:100
Localization:	Cytoplasmic
Tissue Control:	Kidney, Liver, Salivary Gland, Prostate Lesions, P
Species Reactivity:	Human

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Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

AMACR (P504S) is an acronym for the protein alpha-methylacyl CoA racemase that helps to metabolize certain fatty acids within the body. AMACR has been recently described as a prostate cancer-specifi c gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of AMACR protein is found in Prostatic Adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of the prostate: High-Grade Prostatic Intraepithelial Neoplasia (PIN) and Atypical Adenomatous Hyperplasia. Several studies have suggested that AMACR can be used as a prostate cancer biomarker.

High expression of AMACR antibody (P504S) protein is usually found in Prostatic Adenocarcinoma but not in benign prostatic tissue by immunohistochemical staining in paraffin-embedded tissues. Using AMACR as a positive marker along with basal-cell staining (34βE12 or p63) as a negative marker could help to confirm the diagnosis of small foci of Prostate Carcinoma on needle biopsies.

Presentation

AMACRacemase antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Synonyms: AMACR, 2 methylacyl CoA racemase, alpha methylacyl CoA racemase, CBAS4, RACE, RM, AMACRD, amacr, alpha-methylacyl coa racemase, anti-amacr, anti-alpha-methylacyl

Specification Sheets

IVD - CE

Safety Data Sheets

SDS

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Option	SKU	Price
Presentation: 3 ml Predilute	BSB 5057	$224.00
Presentation: 7 ml Predilute	BSB 5058	$371.00
Presentation: 15 ml Predilute	BSB 5059	$669.00
Presentation: .1 ml Concentrate	BSB 5060	$228.00
Presentation: .5 ml Concentrate	BSB 5061	$502.00
Presentation: 1 ml Concentrate	BSB 5062	$765.00
Presentation: Control Slides [5]	BSB-9013-CS	$77.00