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C3d (Polyclonal), RPab

Presentation:

Price: $250.00

SKU:	BSB 6387
Antibody type:	Rabbit Polyclonal
Clone:	Polyclonal
Isotype:	IgG
Concentrate Dilution:	1:100 / 1:500
Localization:	Cytoplasmic, Membranous
Tissue Control:	Kidney Transplant Rejection
Species Reactivity:	Human

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Intended Use

For In Vitro Diagnostic Use.

This antibody is intended for use in Immunohistochemical (IHC) and Immunofluorescence (IF) applications on formalin-fixed paraffin-embedded tissues (FFPE), frozen tissue sections and cell preperations. Interpretation of results should be perfomed by a qualified medical professional.

Summary and Explanation

Complement component 3, or C3, is a protein of the immune system that plays a central role in the complement system and contributes to innate immunity. Its activation is required for both classical and alternative complement activation pathways. C3d deposition in the renal transplant PTCs (peritubular capillaries) is indicative of AR (acute rejection) with subsequent high probability of graft loss.

Anti-C3d combined with anti-C4d can be utilized as a tool for diagnosis of AR and warrant prompt and aggressive anti-rejection treatment. C3d is also a helpful adjunct in the diagnosis of bullous pemphigoid (BP) and perhaps pemphigus vulgaris (PV), especially in the cases in which only formalin-fixed, paraffin embedded tissue is available for analysis.

Presentation

C3d is a purified immunoglobulin fraction of rabbit antiserum that is filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Synonyms: anti-c3d, antic3d, anti c3d, complement component 3

Specification Sheets

IVD - CE

Safety Data Sheets

SDS

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Option	SKU	Price
Presentation: 3 ml Predilute	BSB 6387	$250.00
Presentation: 7 ml Predilute	BSB 6388	$452.00
Presentation: 15 ml Predilute	BSB 6389	$814.00
Presentation: .1 ml Concentrate	BSB 6390	$152.00
Presentation: .5 ml Concentrate	BSB 6391	$372.00
Presentation: 1 ml Concentrate	BSB 6392	$722.00
Presentation: Control Slides [5]	BSB-9043-CS	$77.00

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