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CD33 (RBT-CD33), RMab

Presentation:

Price: $309.00

SKU:	BSB 3448
Antibody type:	Rabbit Monoclonal
Clone:	RBT-CD33
Isotype:	IgG
Concentrate Dilution:	1:10-1:50
Localization:	Membranous
Tissue Control:	Placenta, Myometrium, Lung, Colon
Species Reactivity:	Human

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Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

CD33 (gp62 or siglec-3) is a glycosylated transmembrane protein that is a member of the sialic acid-binding immunoglobulin-like lectin (siglec) family. The genomic locus of this protein has been mapped to chromosome 19q13.1-3.5. The function of CD33 is not known, but it may have a role in cell-to-cell adhesion. In maturing granulocytic cells, there is progressive down-regulation of CD33 from the blast stage to mature neutrophils. However, in monocytes and macrophages/histiocytes, strong expression of CD33 is maintained throughout maturation.

Detection of CD33 using monoclonal antibodies has been a critical component in immunophenotyping acute leukemias, particularly Acute Myeloid Leukemias.

Presentation

CD33 antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Synonyms: CD33 antigen gp67, CD33 molecule, FLJ00391, gp67, Myeloid cell surface antigen CD33, p67, sialic acid binding Ig like lectin 3, Siglec 3, SIGLEC3, anti-cd33, anti cd33

Specification Sheets

IVD - CE

Safety Data Sheets

SDS

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Option	SKU	Price
Presentation: 3 ml Predilute	BSB 3448	$309.00
Presentation: 7 ml Predilute	BSB 3449	$563.00
Presentation: 15 ml Predilute	BSB 3450	$1,009.00
Presentation: .1 ml Concentrate	BSB 3451	$339.00
Presentation: .5 ml Concentrate	BSB 3452	$912.00
Presentation: 1 ml Concentrate	BSB 3453	$1,378.00
Presentation: Control Slides [5]	BSB-9086-CS	$77.00