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CD41 / Integrin alpha IIb (EP178), RMab

Presentation:

Price: $224.00

SKU:	BSB 6506
Antibody type:	Rabbit Monoclonal
Clone:	EP178
Isotype:	IgG
Concentrate Dilution:	1:25-1:100
Localization:	Cytoplasmic, Membranous
Tissue Control:	Spleen, Bone Marrow
Species Reactivity:	Human

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Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

CD41 antibody (ITGA2B antibody) encodes CD41, or integrin alpha IIb. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain IIb undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibrinogen receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface medicated signalling.

CD41 antibody expression has been found on platelets, megakaryocyes, and immature hematopoietic progenitors.

Presentation

CD41 antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Synonyms: GP2B, GPalpha IIb, ITGA2B, sc365938, Integrin αIIb, Integrin alphaIIb, Integrin α IIb, anti-Integrin αIIb, anti Integrin αIIb, Integrin alpha-IIb, anti-GP2B, anti GP2B, anti-ITGA2B, anti ITGA2B, anti-GPalpha IIb, anti GPalpha IIb, anti-Integrin alpha-IIb, anti Integrin alpha-IIb, BDPLT2, CD41, anti-cd41, anti cd41, CD41B, GPIIb, GT, GTA, HPA3, Integrin alpha IIb, Integrin alpha IIb heavy chain, Integrin alpha IIb light chain form 1, Integrin alpha IIb light chain form 2, integrin alpha 2b platelet glycoprotein IIb of IIb IIIa complex antigen CD41, platelet fibrinogen receptor alpha subunit, platelet membrane glycoprotein IIb, platelet specific antigen BAK

Specification Sheets

IVD - CE

Safety Data Sheets

SDS

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Option	SKU	Price
Presentation: 3 ml Predilute	BSB 6506	$224.00
Presentation: 7 ml Predilute	BSB 6507	$404.00
Presentation: 15 ml Predilute	BSB 6508	$726.00
Presentation: .1 ml Concentrate	BSB 6509	$248.00
Presentation: .5 ml Concentrate	BSB 6510	$546.00
Presentation: 1 ml Concentrate	BSB 6511	$834.00
Presentation: Control Slides [5]	BSB 6512	$63.00