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CD43 (MT1), MMab

Presentation:

Price: $124.00

SKU:	BSB 5239
Antibody type:	Mouse Monoclonal
Clone:	MT1
Isotype:	IgG1
Concentrate Dilution:	1:100-1:500
Localization:	Membranous
Tissue Control:	Tonsil, Lymph Node
Species Reactivity:	Human

DescriptionDocumentationAsk a QuestionPrice Details

Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

CD43 (leukosialin, sialophorin, or leukocyte sialoglycoprotein) is one of the major glycoproteins expressed in all thymocytes and T-cells. It plays a role in the physicochemical properties of the T-cell surface and in lectin binding. During T-cell activation, CD43 is actively removed from the T-cell antigen-presenting cell contact site, suggesting a negative regulatory role in adaptive immune response.

CD43 antibody has been found useful in identification and classification of T-cell malignancies and low grade B-cell Lymphomas. CD43 antibody expression is seen in some cases of B-cell Lymphocytic Lymphoma and Centrocytic Lymphoma. When used in combination with CD45 and CD20, effective immunophenotyping of the majority of Lymphomas can be obtained. Co-staining of a lymphoid infiltrate with CD20 and CD3 argues against a reactive process and favors Lymphoma.

Presentation

CD43 antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Synonyms: CD43, Galactoglycoprotein, GALGP, GPL115, Leukocyte sialoglycoprotein, leukosialin, LSN, sialophorin, sialophorin gpL115 leukosialin CD43, sialophorin leukosialin CD43, anti-cd34, anti cd34

Specification Sheets

IVD - CE

Safety Data Sheets

SDS

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Option	SKU	Price
Presentation: 3 ml Predilute	BSB 5239	$124.00
Presentation: 7 ml Predilute	BSB 5240	$188.00
Presentation: 15 ml Predilute	BSB 5241	$348.00
Presentation: .1 ml Concentrate	BSB 5242	$167.00
Presentation: .5 ml Concentrate	BSB 5243	$315.00
Presentation: 1 ml Concentrate	BSB 5244	$466.00
Presentation: Control Slides [5]	BSB-9093-CS	$77.00