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CD8 (C8/144B), MMab

Presentation:

Price: $162.75

SKU:	BSB 5169
Antibody type:	Mouse Monoclonal
Clone:	C8/144B
Isotype:	IgG/K
Concentrate Dilution:	1:250-1:1000
Localization:	Membranous
Tissue Control:	Tonsil, Lymph Node, Liver
Species Reactivity:	Human

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Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

CD8 is a transmembrane glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). Like the TCR, CD8 binds to a major histocompatibility complex (MHC) molecule that is specific for the Class I MHC protein. To function, CD8 forms a dimer, consisting of a pair of CD8 chains. The most common form of CD8 is composed of a CD8-α and CD8-β chain, both members of the immunoglobulin superfamily with an immunoglobulin variable (IgV)-like extracellular domain connected to the membrane by a thin stalk, and an intracellular tail.

CD8 antibody is a T-cell marker for the detection of cytotoxic/suppressor cells of blood lymphocytes. CD8 is also detected on NK cells, most thymocytes, a subpopulation of null cells and bone marrow cells. This antibody is used to distinguish between reactive and neoplastic T-cells.

Presentation

CD8 antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Synonyms: CD8B, CD8B1, CD8A, MAL, anti-CD8, anti CD8, anti-CD8A, anti CD8A, T-lymphocyte differentiation antigen T8/Leu-2, anti-MAL, anti MAL, anti-, anti , anti-T-lymphocyte differentiation antigen T8/Leu-2, anti T-lymphocyte differentiation antigen T8/Leu-2, CD8 antigen beta polypeptide 1 p37, CD8b molecule, Leu2, LY3, LYT3, MGC119115, T lymphocyte surface glycoprotein beta chain, T cell surface glycoprotein CD8 beta chain, CD8, CD8 antigen alpha polypeptide p32, CD8a molecule, Leu2 T lymphocyte antigen, OKT8 T cell antigen, p32, T cell co receptor, T cell antigen Leu2, T cell surface glycoprotein CD8 alpha chain, T lymphocyte differentiation antigen T8 Leu 2, T8 T cell antigen, P37

Specification Sheets

IVD - CE

Safety Data Sheets

SDS

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Option	SKU	Price
Presentation: 3 ml Predilute	BSB 5169	$162.75
Presentation: 7 ml Predilute	BSB 5170	$279.30
Presentation: 15 ml Predilute	BSB 5171	$446.25
Presentation: .1 ml Concentrate	BSB 5172	$152.25
Presentation: .5 ml Concentrate	BSB 5173	$390.60
Presentation: 1 ml Concentrate	BSB 5174	$606.90
Presentation: Control Slides [5]	BSB 5175	$67.00