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CDK2 (RBT-CDK2), RMab

Presentation:

Price: $203.00

SKU:	BSB 2636
Antibody type:	Rabbit Monoclonal
Clone:	RBT-CDK2
Isotype:	IgG
Concentrate Dilution:	1:25-1:100
Localization:	Nuclear
Tissue Control:	Testis, Tonsil, Prostate, Placenta
Species Reactivity:	Human

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Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

CDK2 (also known as Cyclin-dependent kinase 2 or cell division protein kinase 2) is a 33 kDa enzyme that in humans is encoded by the CDK2 gene on Chromosome 12. CDK2 is a catalytic subunit of the cyclin-dependent kinase complex, whose activity is restricted to the G1-S phase of the cell cycle, and is essential for the cellular G1/S transition.

Studies indicate that over expression of CDK2 may cause the abnormal regulation of cell-cycle, which would could directly contribute to hyper-proliferation of cancerous cells. HOX genes, which play a key role in cell differentiation and morphogenisis, are regulated by CDK2. Studies have shown that HOXA7 promoted cell proliferation (mediated by cyclin E1/CDK2) is evident in cases of Hepatocellular carcinoma, indicating that CDK2 antibody may prove to be a useful marker in such cases.

Presentation

CDK2 antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, fi lter sterilized and diluted in buff er pH 7.5, containing BSA and sodium azide as a preservative.

Synonyms: CDK2, cyclin dependent kinase 2, sc6248, Cdk 2, anti-Cdk2, anti Cdk2, anti-cyclin dependent kinase 2, anti cyclin dependent kinase 2, cdc2 related protein kinase, cell devision kinase 2, Cell division protein kinase 2, p33 protein kinase, p33 CDK2

Specification Sheets

IVD - CE

Safety Data Sheets

SDS

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Option	SKU	Price
Presentation: 3 ml Predilute	BSB 2636	$203.00
Presentation: 7 ml Predilute	BSB 2637	$496.00
Presentation: 15 ml Predilute	BSB 2638	$980.00
Presentation: .1 ml Concentrate	BSB 2639	$233.00
Presentation: .5 ml Concentrate	BSB 2640	$673.00
Presentation: 1 ml Concentrate	BSB 2641	$1,011.00
Presentation: Control Slides [5]	BSB-9114-CS	$99.00