Navigate:

StoreFront / Immunohistochemistry / Antibodies / All Antibodies / CDK4 (EP180), RMab

<		Previous Product
		Next Product		>

CDK4 (EP180), RMab

Presentation:

Price: $199.00

SKU:	BSB 2461
Antibody type:	Rabbit Monoclonal
Clone:	EP180
Isotype:	IgG
Concentrate Dilution:	1:25-1:100
Localization:	Nuclear
Tissue Control:	Cervical and Colon Cancer
Species Reactivity:	Human

DescriptionDocumentationAsk a QuestionPrice Details

Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

Cyclin-dependent kinase 4 (CDK4) is a member of the Ser/Thr protein kinase family. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16 (INK4a).

Overexpression of CDK4 antibody has been observed in many tumor types, including oral squamous cell carcinoma and cancers of the pancreatic (endocrine tumors), lung, breast and colon. The expression of CDK4 antibody is associated with tumor progression. Binh et al. reported a high expression of CDK4 (92%) in atypical lipomatous tumor/well-differentiated liposarcomas (ALT-WDLPS) and dedifferentiated liposarcomas (DDLPS). CDK4 is useful in differentiating ALT-WDLPS from benign adipose tumors and to separate DDLPS from poorly differentiated sarcomas.

Presentation

CDK4 antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, fi lter sterilized and diluted in buff er pH 7.5, containing BSA and sodium azide as a preservative.

Synonyms: CDK4, Cdk 4, anti-Cdk4, anti Cdk4, Cyclin-dependent kinase 4, anti-Cyclin-dependent kinase 4, anti Cyclin-dependent kinase 4, cell division protein kinase 4, CMM3, cyclin dependent kinase 4, MGC14458, PSK J3

Specification Sheets

IVD - CE

Safety Data Sheets

SDS

There are currently no questions about this product.
Ask a Question

Option	SKU	Price
Presentation: 3 ml Predilute	BSB 2461	$199.00
Presentation: 7 ml Predilute	BSB 2462	$487.00
Presentation: 15 ml Predilute	BSB 2463	$963.00
Presentation: .1 ml Concentrate	BSB 2464	$230.00
Presentation: .5 ml Concentrate	BSB 2465	$662.00
Presentation: 1 ml Concentrate	BSB 2466	$995.00
Presentation: Control Slides [5]	BSB-9115-CS	$77.00