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FOXP3 (EP340), RMab
| SKU: |
BSB 2922 |
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Antibody type:
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Rabbit Monoclonal
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Clone:
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EP340
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Isotype:
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IgG
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Concentrate Dilution:
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1:25-1:100
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Localization:
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Nuclear
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Tissue Control:
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Tonsil, Lymph Node, Thymus, Colon
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Species Reactivity:
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Human
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Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
FOXP3, also known as scurfin, is a protein involved in immune system responses. A member of the forkhead box protein family, FOXP3 appears to function as a transcription factor in the development and function of regulatory T cells. In regulatory T cell model systems, the FOXP3 transcription factor occupies the promoters of many important for regulatory T-cell function, and may repress transcription of key genes following stimulation of T cell receptors.
Alterations in numbers of regulatory T-cells – in particular those that express FOXP3 antibody – are found in a number of disease states. Patients with tumors have a local relative excess of FOXP3 positive T cells which inhibits the body’s ability to suppress the formation of cancerous cells.
Presentation
FOXP3 antibody s a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: FOXP3, anti-FOXP3, anti FOXP3, forkhead box P3 (FOXP3), anti-forkhead box P3 (FOXP3), anti forkhead box P3 (FOXP3), forkhead/winged-helix transcription regulator family member FOXP3 (forkhead box P3), X-linked syndrome (IPEX) related, anti-forkhead/winged-helix transcription regulator family member FOXP3 (forkhead box P3), anti forkhead/winged-helix transcription regulator family member FOXP3 (forkhead box P3), anti-X-linked syndrome (IPEX) related, anti X-linked syndrome (IPEX) related, AIID, DIETER, forkhead box P3, Forkhead box protein P3, immune dysregulation polyendocrinopathy enteropathy X linked, immunodeficiency polyendocrinopathy enteropathy X linked, IPEX, JM2, MGC141961, MGC141963, PIDX, Scurfin, XPID, FOXP3delta7, foxp
Specification Sheets
Safety Data Sheets
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| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 2922 | $286.00 |
| Presentation: 7 ml Predilute | BSB 2923 | $429.00 |
| Presentation: 15 ml Predilute | BSB 2924 | $716.00 |
| Presentation: .1 ml Concentrate | BSB 2925 | $286.00 |
| Presentation: .5 ml Concentrate | BSB 2926 | $574.00 |
| Presentation: 1 ml Concentrate | BSB 2927 | $1,002.00 |
| Presentation: Control Slides [5] | BSB-9186-CS | $77.00 |
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