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IGN-y, IFNy, IFN y, anti-ifn-y, anti-ifny, anti-ifn y, gamma, ifn-gamma, ifn gamma, anti-ifn-gamma, IGN-y, IFNy, IFN y, MAIN

IFN-y (BSB-161), MMab

Presentation:

Price: $184.80

SKU:	BSB-3734-3
Antibody type:	Mouse Monoclonal
Clone:	BSB-161
Isotype:	IgG2a
Concentrate Dilution:	1:50-1:200
Localization:	Cytoplasmic, Membranous
Tissue Control:	Stomach, Falopian Tube, Colon
Species Reactivity:	Human

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Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

IFN-γ is a dimerized soluble cytokine and the only member of the type II interferon. In humans, IFN-γ is encoded by the IFNG gene and is critical for innate and adaptive immunity against viral, some bacterial and protozoal infections. IFN-γ is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 Th1 and CD8 cytotoxic T lymphocytes effector T cells once antigen-specific immunity develops as part of the adaptive immune response. IFN-γ is also produced by non-cytotoxic innate lymphoid cells.

IFN-γ interacts with its receptors interferon gamma receptor 1 and interferon gamma receptor 2 and activates them. IFN-γ binding to the receptors activates the JAK-STAT pathway. IFN-γ also binds to the glycosaminoglycan heparan sulfate and inhibits its biological activity. IFN-γ is used to treat Chronic Granulomatous Disease and Osteopetrosis, also has potential as cancer immunotherapy to improve survival in Bladder Carcinoma, Melanoma, and Ovarian Carcinoma.

Synonyms: IGN-y, IFNy, IFN y, anti-ifn-y, anti-ifny, anti-ifn y, gamma, ifn-gamma, ifn gamma, anti-ifn-gamma

Specification Sheets

IVD

Safety Data Sheets

SDS

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Option	SKU	Price
Presentation: 3 ml Predilute	BSB-3734-3	$184.80
Presentation: 7 ml Predilute	BSB-3734-7	$330.75
Presentation: 15 ml Predilute	BSB-3734-15	$581.70
Presentation: .1 ml Concentrate	BSB-3734-01	$192.15
Presentation: .5 ml Concentrate	BSB-3734-05	$416.85
Presentation: 1 ml Concentrate	BSB-3734-1	$661.50
Presentation: Control Slides [5]	BSB-9232-CS	$67.00

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IFN-y (BSB-161), MMab

Intended Use

Summary and Explanation

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