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MCM3 (EP202), RMab

Presentation:

Price: $266.00

SKU:	BSB 6884
Antibody type:	Rabbit Monoclonal
Clone:	EP202
Isotype:	IgG
Concentrate Dilution:	1:25-1:100
Localization:	Nuclear
Tissue Control:	Colon Carcinoma
Species Reactivity:	Human, Predicted: Mouse, Rat

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Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

MCM3 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication proteins. MCM3 is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progrsession.

Increased expression of MCM3 antibody has been demonstrated in various tymors by immunohistochemistry and is used as a marker for tumor progression.

Presentation

MCM3 antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Synonyms: MCM3, anti-MCM3, anti MCM3, minichromosome maintenance complex component 3, HCC5, P1 MCM3, P1 h, RLFB, mcm-3, anti-mcm-3, anti mcm-3

Specification Sheets

IVD - CE

Safety Data Sheets

SDS

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Option	SKU	Price
Presentation: 3 ml Predilute	BSB 6884	$266.00
Presentation: 7 ml Predilute	BSB 6885	$483.00
Presentation: 15 ml Predilute	BSB 6886	$773.00
Presentation: .1 ml Concentrate	BSB 6887	$189.00
Presentation: .5 ml Concentrate	BSB 6888	$423.00
Presentation: 1 ml Concentrate	BSB 6889	$786.00
Presentation: Control Slides [5]	BSB 6890	$63.00