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Melanoma PNL2 (PNL2), MMab

Presentation:

Price: $163.00

SKU:	BSB 6912
Antibody type:	Mouse Monoclonal
Clone:	PNL2
Isotype:	IgG1
Concentrate Dilution:	1:100-1:500
Localization:	Cytoplasmic
Tissue Control:	Melanoma
Species Reactivity:	Human, Dog

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Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

PNL2 antibody reacts against an antigen present in melanocytic tumors such as Melanomas. The antibody was generated to an extract of Melanoma. It reacted positively against Melanocytic Tumors but not other tumors, thus demonstrating specificity and sensitivity. Moreover, this antibody reacts positively against junctional nevus cells but not intradermal nevi, and against fetal melanocytes but not normal adult melanocytes.

PNL2 antibody is very useful to identify Malignant Melanoma. Metastatic Amelanotic Melanoma can often be confused with a variety of poorly differentiated Carcinomas, Large Cell Lymphomas, Sarcomas, Spindle Cell Carcinomas and various types of mesenchymal neoplasms. A keratin-negative, vimentin-rich neoplasm that immunoreacts with antibody to S-100 protein and with this melanoma antibody, is, with rare exception, a Melanoma.

Presentation

Melanoma antibody (PNL2) is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Synonyms: S 100 protein, S100, HMB 45, Melan A, Mitf, microphthalmia transcription factor, MART 1, human melanoma black 45, anti-melanoma, anti-pnl2, anti pnl2

Specification Sheets

IVD - CE

Safety Data Sheets

SDS

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Option	SKU	Price
Presentation: 3 ml Predilute	BSB 6912	$163.00
Presentation: 7 ml Predilute	BSB 6913	$296.00
Presentation: 15 ml Predilute	BSB 6914	$529.00
Presentation: .1 ml Concentrate	BSB 6915	$183.00
Presentation: .5 ml Concentrate	BSB 6916	$400.00
Presentation: 1 ml Concentrate	BSB 6917	$606.00
Presentation: Control Slides [5]	BSB-9275-CS	$77.00