Navigate:

StoreFront / Immunohistochemistry / Antibodies / All Antibodies / Pygopus 2 (BSB-156), MMab

<		Previous Product
		Next Product		>

pygopus 2, pygo2, anti-pygopus 2, pygopus-2, anti-pygo2, anti-pygo 2, pygo 2, anti pygo-2, pygo-2 MAIN

Pygopus 2 (BSB-156), MMab

Presentation:

Price: $176.00

SKU:	BSB-3745-3
Antibody type:	Mouse Monoclonal
Clone:	BSB-156
Isotype:	IgG2a
Concentrate Dilution:	1:50-1:200
Localization:	Cytoplasmic. Membranous, Nuclear
Tissue Control:	Fallopian Tube, Adrenal Gland, Kidneys
Species Reactivity:	Human, Mouse, Rat

DescriptionDocumentationAsk a QuestionPrice Details

Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

Pygopus Family PHD Finger 2 (PYGO2) is a protein-coding gene associated with G-protein coupled receptor (GPCR) and Wnt signaling pathways, chromatin binding and histone acetyltransferase regulator activity. Pygo2 as a Wnt signaling pathway component has been detected in multiple cancer types.

One study found that abnormal Pygopus 2 antibody expression was associated with poor differentiation and a high tumor, node, and metastases stage and poor prognosis in non-small cell lung cancer (NSCLC) patients, therefore abnormal Pygo2 qntibody expression may be a marker for advanced NSCLC. Another study found that 59% of the patient tumor specimens exhibited positive Pygopus 2 antibody immunohistochemistry staining and increased intensity with the grade of malignancy, especially for WHO grade III and IV.

High-level expression has been reported in gliomas compared with normal brain tissues, which suggest an important role of Pygo2 in brain tumor progression. In a Colorectal Cancer study, the expression pattern of Pygo2 was evaluated by immunohistochemistry in tumor tissues and their normal margins, and found the expression of pygopus 2 antibody was detected in all tumor tissues. Furthermore, this expression was significantly higher in Colorectal Cancer samples than in normal tissues, and a significant association was found between Pygo2 protein expression in Colorectal Cancer and tumor cell metastasis to the lymph nodes. Pygo2 is also associated with Oligospermia

Synonyms: pygopus 2, pygo2, anti-pygopus 2, pygopus-2, anti-pygo2, anti-pygo 2, pygo 2, anti pygo-2, pygo-2

Specification Sheets

IVD

Safety Data Sheets

SDS

There are currently no questions about this product.
Ask a Question

Option	SKU	Price
Presentation: 3 ml Predilute	BSB-3745-3	$176.00
Presentation: 7 ml Predilute	BSB-3745-7	$315.00
Presentation: 15 ml Predilute	BSB-3745-15	$554.00
Presentation: .1 ml Concentrate	BSB-3745-01	$183.00
Presentation: .5 ml Concentrate	BSB-3745-05	$397.00
Presentation: 1 ml Concentrate	BSB-3745-1	$630.00
Presentation: Control Slides [5]	BSB-3745-CS	$63.00

(805) 692-2768

sales@biosb.com

Returning Customer?

Shopping Cart

The Shopping Cart is currently empty

Enter Coupon

Secure Checkout

Pygopus 2 (BSB-156), MMab

Intended Use

Summary and Explanation

Subscribe to our mailing list