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TTF-1 (8G7G3/1), MMab

Presentation:

Price: $135.00

SKU:	BSB 6001
Antibody type:	Mouse Monoclonal
Clone:	8G7G3/1
Isotype:	IgG1
Concentrate Dilution:	1:250-1:1000
Localization:	Nuclear
Tissue Control:	Lung, Thyroid, Adenocarcinoma of Lung
Species Reactivity:	Human, Dog

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Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

Thyroid transcription factor-1 (TTF-1) is a protein that regulates transcription of genes specific to the thyroid, lung and diencephalon. It is also known as thyroid-specific enhancer binding protein and NKX-2. It is used as a marker to determine if a tumor oringinates in the lung or thyroid. TTF-1 positive cells are found in Type II pneumocytes and Clara cells in the lung. In the thyroid, follicular and parafollicular cells are positive.

TTF-1 antibody is useful in differentiating primary Adenocarcinoma of the Lung from Metastatic Carcinomas of the breast and Malignant Mesothelioma. It can also be used to differentiate Small- Cell Lung Carcinoma from lymphoid infiltrates. For lung cancers, Adenocarcinomas are usually positive, while Squamous Cell Carcinomas and Large Cell Carcinomas are rarely positive. Small-Cell Carcinomas (of any primary site) are usually positive.

Presentation

TTF-1 antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Synonyms: TTF 1, TTF1, NKX2-1, anti-TTF-1, anti TTF-1, anti-TTF 1, anti-TTF1, anti TTF 1, anti TTF1, Homeobox protein Nkx 2 1, NK2 homeobox 1, Nkx2 1, thyroid nuclear factor 1, Thyroid transcription factor 1, thyroid transcription factor 1 TTF 1 NK 2, Titf1

Specification Sheets

IVD - CE

Safety Data Sheets

SDS

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Option	SKU	Price
Presentation: 3 ml Predilute	BSB 6001	$135.00
Presentation: 7 ml Predilute	BSB 6002	$158.00
Presentation: 15 ml Predilute	BSB 6003	$300.00
Presentation: .1 ml Concentrate	BSB 6004	$167.00
Presentation: .5 ml Concentrate	BSB 6005	$344.00
Presentation: 1 ml Concentrate	BSB 6006	$602.00
Presentation: Control Slides [5]	BSB 6007	$77.05