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Tyrosinase (BSB-6), MMab

Presentation:

Price: $188.00

SKU:	BSB 6008
Antibody type:	Mouse Monoclonal
Clone:	BSB-6
Isotype:	IgG2a
Concentrate Dilution:	1:50-1:200
Localization:	Cytoplasmic
Tissue Control:	Skin, Malignant Melanoma
Species Reactivity:	Human

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Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

Tyrosinase is an enzyme that catalyzes the oxidation of phenols (such as tyrosine) and is widespread in plants and animals. Tyrosinase is a copper-containing enzyme present in plant and animal tissues that catalyzes the production of melanin and other pigments from tyrosine by oxidation. The gene for Tyrosinase is regulated by the Microphthalmia-associated transcription factor. A mutation in the tyrosinase gene leads to impaired tyrosinase production resulting in Type I Oculocutaneous Albinism, a hereditary disease that affects 1 in 17,000 people in the U.S.

Tyrosinase antibody has been found to be quite specific for melanotic lesions such as Malignant Melanoma and Melanotic Neurofibroma. Essentially no carcinomas express this marker.

Presentation

Tyrosinase antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Synonyms: TYR, santi-Tyrosinase, anti Tyrosinase, anti-TYR, anti TYR, LB24 AB, Monophenol monooxygenase, OCA1A, OCAIA, SHEP3, SK29 AB, tumor rejection antigen AB, Tyrosinase, tyrosinase oculocutaneous albinism IA, Tyrosinase precursor, Albino locus protein, CMM8

Specification Sheets

IVD - CE

Safety Data Sheets

SDS

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Option	SKU	Price
Presentation: 3 ml Predilute	BSB 6008	$188.00
Presentation: 7 ml Predilute	BSB 6009	$344.00
Presentation: 15 ml Predilute	BSB 6010	$602.00
Presentation: .1 ml Concentrate	BSB 6011	$167.00
Presentation: .5 ml Concentrate	BSB 6012	$376.00
Presentation: 1 ml Concentrate	BSB 6013	$589.00
Presentation: Control Slides [5]	BSB-9423-CS	$77.00