Zap-70 (2F3.2), MMab

Presentation:

Price: $172.00

SKU:	BSB 6036
Antibody type:	Mouse Monoclonal
Clone:	2F3.2
Isotype:	IgG2a
Concentrate Dilution:	1:250-1:1000
Localization:	Cytoplasmic
Tissue Control:	Tonsil, Lymph Node, Thymus, Chronic Lymphocytic Le
Species Reactivity:	Human

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Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

ZAP-70 is an abbrevation for Zeta-chain-associated protein kinase 70 (70 is the molecular weight in kDa). The protein is a member of the protein-tyrosine kinase family. ZAP-70 is normally expressed in T-cells and natural killer cells and has a critical role in the initiation of T-cell signaling. ZAP-70 in B-cells is used as a prognostic marker in identifying different forms of Chronic Lymphocytic Leukemia (CLL). ZAP-70 protein is expressed in leukemic cells in approximately 25% of Chronic Lymphocytic Leukemia (CLL) cases as well. ZAP-70 expression is an excellent surrogate marker for the distinction between the Ig-mutated (ZAP-70 negative) and Ig-unmutated (ZAP-70 positive) CLL subtypes and can identify patient groups with divergent clinical courses. The ZAP-70 positive Ig-unmutated CLL cases have a poorer prognosis.

Presentation

ZAP-70 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Specification Sheets

IVD - CE

RUO

Safety Data Sheets

SDS

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Option	SKU	Price
Presentation: 3 ml Prediluted	BSB 6036	$172.00
Presentation: 7 ml Prediluted	BSB 6037	$310.00
Presentation: 15 ml Prediluted	BSB 6038	$558.00
Presentation: .1 ml Concentrated	BSB 6039	$130.00
Presentation: .5 ml Concentrated	BSB 6040	$354.00
Presentation: 1 ml Concentrated	BSB 6041	$472.00
Presentation: Control Slides [5]	BSB 6042	$60.00