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CD68 (KP-1), MMab
SKU: |
BSB 2712 |
Antibody type:
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Mouse Monoclonal
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Clone:
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KP-1
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Isotype:
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IgG1/K
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Concentrate Dilution:
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1:250-1:1000
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Localization:
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Cytoplasmic, Membranous
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Tissue Control:
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Tonsil, Lymph Node
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Species Reactivity:
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Human, Hamster, Mouse, Non-Human Primate
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Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
The CD68 antigen is a heavily glycosylated transmembrane protein of 87-115 kDa which is specifically expressed by tissue macrophages, Langerhans cells and, at low levels, by dendriticcells. CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracel-lular cell-cell and cell-pathogen interactions.
CD68 antibody marks cells of monocyte/macrophage lineage. This antibody is capable of staining monocytes, Kupffer cells, osteoclasts, granulocytes and their precursors; Lymphomas are negative or show a few granules. This antibody may be useful for the identification of Myelomonocytic and Histiocytic Tumors. The CD68 antibody may help to distinguish Malignant Fibrous Histiocytoma from other Pleomorphic Sarcomas. However, since CD68 detects a formalin-resistant epitope that may be associated with lysosomal granules, other lysosome-rich cells may also produce positive results.
Presentation
CD68 antibody is a mouse monoclonal antibody derived from cell culture supernatant that
is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing
BSA and sodium azide as a preservative.
Synonyms: CD68, Gp110, SCARD1, LAMP4, anti-CD68, anti CD68, anti-GP110, anti GP110, anti-LAMP4, anti LAMP4, anti-SCARD1, anti SCARD1, CD68 antigen, CD68 molecule, DKFZp686M18236, macrophage antigen CD68, macrosialin, scavenger receptor class D member 1
Specification Sheets
Safety Data Sheets
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Option | SKU | Price |
Presentation: 3 ml Predilute | BSB 2712 | $131.25 |
Presentation: 7 ml Predilute | BSB 2713 | $154.35 |
Presentation: 15 ml Predilute | BSB 2714 | $301.35 |
Presentation: .1 ml Concentrate | BSB 2715 | $143.85 |
Presentation: .5 ml Concentrate | BSB 2716 | $255.15 |
Presentation: 1 ml Concentrate | BSB 2717 | $451.50 |
Presentation: Control Slides [5] | BSB 2718 | $67.00 |
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