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Factor XIIIa (EP292), RMab
| SKU: |
BSB 5505 |
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Antibody type:
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Rabbit Monoclonal
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Clone:
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EP292
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Isotype:
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IgG
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Concentrate Dilution:
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1:50-1:200
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Localization:
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Cytoplasmatic
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Tissue Control:
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Placenta, Colon, Adrenal,Testis, Dermatofibroma
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Species Reactivity:
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Human
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Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
Factor XIII or fibrin stabilizing factor is an enzyme of the blood coagulation system that crosslinks fibrin. When thrombin has converted fibrinogen to fibrin, the latter forms a proteinaceous network in which every E-unit is crosslinked to only one D-unit. Factor XIII is activated by thrombin into Factor XIIIa; its activation into Factor XIIIa requires calcium as a cofactor. Factor XIIIa has been identified in platelets, megakaryocytes, and fibroblast-like mesenchymal or histiocytic cells present in the placenta, uterus, and prostate; it is also present in monocytes, macrophages and dermal dendritic cells.
Factor XIIIa antibody has been found to be useful in differentiating between Dermatofibroma (90% (+)), Dermatofibrosarcoma Protuberans (25%(+)) and Desmoplastic Malignant Melanoma (0%(+)). Factor XIIIa positivity is also seen in Capillary Hemagioblastoma (100%(+)), Hemangioendothelioma (100%(+)), Hemangiopericytoma (100%(+)), Xanthogranuloma (100%(+)), Xanthoma (100(+)), Hepatocellular Carcinoma (93%(+)), Glomus Tumor (80%(+)), and Meningioma 80%(+)).
Presentation
Factor XIIIa antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: bA525O21 1 coagulation factor XIII A1 polypeptide, Coagulation factor XIII A chain, coagulation factor XIII A polypeptide, coagulation factor XIII A1 polypeptide, coagulation factor XIIIa, F13A, factor XIIIa, anti-factor xiiia, anti factor xiiia, anti-factor 13a, anti factor 13a, fibrin stabilizing factor A subunit, fibrinoligase, FSF A subunit, protein glutamine gamma glutamyltransferase A chain, TGase, Transglutaminase A chain, transglutaminase plasma
Specification Sheets
Safety Data Sheets
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| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 5505 | $143.00 |
| Presentation: 7 ml Predilute | BSB 5506 | $269.00 |
| Presentation: 15 ml Predilute | BSB 5507 | $521.00 |
| Presentation: .1 ml Concentrate | BSB 5508 | $171.00 |
| Presentation: .5 ml Concentrate | BSB 5509 | $367.00 |
| Presentation: 1 ml Concentrate | BSB 5510 | $576.00 |
| Presentation: Control Slides [5] | BSB-9176-CS | $77.00 |
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