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S100A8 / MRP8 (EP90), RMab
| SKU: |
BSB 2356 |
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Antibody type:
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Rabbit Monoclonal
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Clone:
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EP90
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Isotype:
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IgG
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Concentrate Dilution:
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1:10-1:50
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Localization:
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Cytoplasmic, Nuclear
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Tissue Control:
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Tonsil, Breast, Liver, Fallopian Tube
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Species Reactivity:
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Human, Predicted: Mouse
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Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
Myeloid Related Protein 8 (MRP8), also known as S100A8, is a calcium binding protein that belongs to the S100 family. By a Ca2+ dependent manner, S100A8/A9 forms Calprotectin, a heterodimeric inflammatory mediator of inflammation found in the cytoplasm of neutrophils and expressed on the membrane of monocytes. S100A8 is expressed during myeloid differentiation and chronic inflammations, and it is expressed constitutively or induced in epithelial cells during dermatose.
S100A8 antibody is expressed in cells with myeloid origin, including granulocytes, monocytes and macrophages, and it is observed in blood granulocytes and monocytes. It is also expressed in infiltrate macrophages during inflammatory reactions, but not in normal tissue macrophages. S100A8 antibody also reacts with activated microglial cells in human cerebral malaria. In tumors, positive staining of S100A8 has been observed in various cancers including pancreatic cancer, and it has been linked to inflammation-associated cancers.
Presentation
S100A8 antibody (MPR8 antibody) is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: S100A8, santi-Calgranulin A, anti Calgranulin A, anti-S100A8, anti S100A8, Cystic fibrosis antigen (CFAG), anti-Cystic fibrosis antigen (CFAG), anti Cystic fibrosis antigen (CFAG), 60B8AG, CAGA, calgranulin A, calprotectin L1L subunit, CFAG, CGLA, CP 10, Cystic fibrosis antigen, L1Ag, leukocyte L1 complex light chain, MA387, MIF, Migration inhibitory factor related protein 8, MRP 8, MRP8, NIF, p8, Protein S100 A8, S100 calcium binding protein A8, S100 calcium binding protein A8 calgranulin A, Urinary stone protein band A
Specification Sheets
Safety Data Sheets
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| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 2356 | $314.00 |
| Presentation: 7 ml Predilute | BSB 2357 | $570.00 |
| Presentation: 15 ml Predilute | BSB 2358 | $912.00 |
| Presentation: .1 ml Concentrate | BSB 2359 | $223.00 |
| Presentation: .5 ml Concentrate | BSB 2360 | $500.00 |
| Presentation: 1 ml Concentrate | BSB 2361 | $928.00 |
| Presentation: Control Slides [5] | BSB 2362 | $77.05 |
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